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Analysis of Pediatric Pancreatitis (APPLE trial): Pre-study protocol of a multinational prospective clinical trial.

Background: Single-centered studies show increased incidence of acute pancreatitis (AP) in children. Here, the Pediatric Section of the Hungarian Pancreatic Study Group introduce an international observational clinical trial (APPLE) to collect a critical mass...

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Early Achievable SeveritY (EASY) index for simple and accurate expedite risk stratification in acute pancreatitis

Background: Acute pancreatitis (AP) is one of the most common diseases of the gastrointestinal tract associated with significant morbidity and mortality. The assessment of severity is crucial in the management of the disease. Current methods of risk stratification...

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Natural History of Serous Cystadenomas

Serous cystadenomas (SC) represent 30% of pancreatic cystic lesions. Their histological, epidemiological and semiological characteristics are now better known. However, their natural history remains poorly understood affecting therapeutic management as well.

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Pain IN the EArly phase of Pediatric Pancreatitis (PINEAPPLE trial): Pre-study protocol of a multinational prospective clinical trial.

Background: There are unexpectedly large differences between the incidences of AP among the hospitals. Retrospective studies suggesting that the reason behind this is the large differences between the local managements of abdominal pain at emergency units. Unfortunately,...

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